Cadmium poisoning

Summary about Disease


Cadmium poisoning is a condition caused by the accumulation of cadmium in the body. Cadmium is a toxic heavy metal found in the environment and used in various industrial processes. Exposure can occur through inhalation, ingestion, or skin contact. Chronic exposure can lead to serious health problems affecting the kidneys, bones, and lungs.

Symptoms


Acute exposure (high levels): Nausea, vomiting, abdominal cramps, diarrhea, muscle cramps, salivation. Severe cases can lead to kidney failure, liver damage, and even death.

Chronic exposure (long-term, low levels): Kidney dysfunction (proteinuria, glucosuria), bone demineralization (osteomalacia, osteoporosis), lung damage (emphysema), increased risk of certain cancers.

Causes


Occupational exposure: Mining, smelting, electroplating, battery manufacturing, pigment production.

Environmental exposure: Contaminated food (especially shellfish, rice, and leafy vegetables grown in contaminated soil), contaminated drinking water, air pollution from industrial sources.

Smoking: Tobacco plants absorb cadmium from the soil, so smoking is a significant source of cadmium exposure.

Ingestion of cadmium-contaminated food or water.

Medicine Used


Chelation therapy: Medications like EDTA (ethylenediaminetetraacetic acid) or succimer (DMSA) may be used to bind to cadmium and promote its excretion from the body. However, chelation is most effective shortly after exposure and is less effective for chronic exposure.

Supportive care: Treatment focuses on managing symptoms and complications, such as kidney failure or bone problems. This might involve dialysis, pain medication, and medications to strengthen bones.

Is Communicable


No, cadmium poisoning is not communicable. It cannot be spread from person to person. It is caused by exposure to cadmium in the environment or workplace.

Precautions


Workplace safety: Implementing and enforcing strict safety measures in industries that use cadmium, including ventilation, personal protective equipment (respirators, gloves, protective clothing), and regular monitoring of cadmium levels in the air.

Environmental monitoring: Monitoring cadmium levels in soil, water, and air, especially near industrial sites. Remediation of contaminated sites.

Food safety: Avoiding consumption of food grown in contaminated soil or water. Careful sourcing of seafood.

Smoking cessation: Quitting smoking reduces cadmium exposure.

Water Filtration: Using water filter certified to remove heavy metals like cadmium can help reduce exposure via drinking water.

How long does an outbreak last?


Cadmium poisoning doesn't typically occur in "outbreaks" in the infectious disease sense. Acute cadmium poisoning lasts until the cadmium is cleared from the body and symptoms subside with treatment, potentially days to weeks depending on exposure level and treatment effectiveness. Chronic cadmium poisoning is a long-term condition resulting from continued exposure, and the effects can persist for years or even a lifetime, even after exposure is stopped.

How is it diagnosed?


Blood test: Measures cadmium levels in the blood. Most useful for recent exposures.

Urine test: Measures cadmium levels in the urine. Indicates both recent and long-term exposure.

Hair and nail analysis: Can indicate long-term exposure, but accuracy can be affected by external contamination.

Kidney function tests: To assess kidney damage (e.g., creatinine, BUN, proteinuria).

Bone density scans: To assess bone mineral density.

Medical history and physical examination: To evaluate symptoms and potential sources of exposure.

Timeline of Symptoms


Acute Exposure: Symptoms can appear within minutes to hours after ingestion or inhalation of high levels of cadmium.

Chronic Exposure: Symptoms develop gradually over years of exposure. Early signs may be subtle (e.g., mild proteinuria) and may not be noticed until significant kidney or bone damage has occurred.

Important Considerations


Vulnerable populations: Children, pregnant women, and individuals with pre-existing kidney or bone conditions are particularly vulnerable to the effects of cadmium poisoning.

Long-term health effects: Even after exposure is stopped, the effects of chronic cadmium poisoning can persist and increase the risk of developing certain cancers, kidney failure, and bone fractures.

Prevention is key: Reducing exposure to cadmium through workplace safety measures, environmental monitoring, and lifestyle choices (e.g., not smoking) is the best way to prevent cadmium poisoning.