Fatigue syndrome

Summary about Disease


Fatigue syndrome, also known as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), is a complex, chronic, and debilitating disease characterized by profound fatigue that is not improved by rest and worsens after physical or mental activity (post-exertional malaise). It affects multiple body systems and significantly impairs daily functioning.

Symptoms


Overwhelming fatigue that lasts for at least six months

Post-exertional malaise (PEM): Worsening of symptoms after physical or mental exertion

Unrefreshing sleep

Cognitive difficulties (brain fog): Problems with memory, concentration, and thinking

Orthostatic intolerance: Dizziness or lightheadedness upon standing

Muscle pain

Joint pain

Headaches

Sore throat

Tender lymph nodes

Digestive problems

Causes


The exact cause of ME/CFS is unknown. Research suggests a combination of factors may be involved, including:

Viral infections

Immune system dysfunction

Hormonal imbalances

Genetic predisposition

Psychological stress

Medicine Used


There is no cure for ME/CFS, and treatment focuses on managing symptoms. Common medications used may include:

Pain relievers (e.g., acetaminophen, ibuprofen)

Sleep aids (e.g., melatonin, prescription medications)

Antidepressants (to treat depression and pain)

Medications for orthostatic intolerance (e.g., fludrocortisone, midodrine)

Other medications to address specific symptoms (e.g., medications for headaches, digestive problems)

Is Communicable


ME/CFS is not considered to be a communicable disease. It is not contagious and cannot be spread from person to person through typical means like coughs or sneezes.

Precautions


Since the cause is unknown, specific precautions to prevent ME/CFS are not well-defined. However, general health recommendations include:

Managing stress

Getting adequate sleep

Maintaining a healthy diet

Avoiding overexertion For people with ME/CFS: *Pacing activities (balancing rest and activity)* *Avoiding triggers for symptom exacerbation.*

How long does an outbreak last?


ME/CFS is a chronic condition, not an "outbreak". People live with this condition long-term, sometimes for many years or even a lifetime. Symptom severity can fluctuate over time.

How is it diagnosed?


Diagnosis is based on clinical evaluation, as there are no specific diagnostic tests. Diagnosis typically involves:

Ruling out other conditions with similar symptoms.

Meeting specific diagnostic criteria (e.g., the Institute of Medicine criteria or the Canadian Consensus Criteria).

A thorough medical history and physical examination.

Assessment of symptoms (fatigue, PEM, unrefreshing sleep, cognitive impairment).

Timeline of Symptoms


The onset of symptoms can vary. Some people experience a sudden onset after an illness (such as a viral infection), while others develop symptoms gradually over time. The course of the illness is often characterized by periods of remission and relapse.

Important Considerations


ME/CFS is a complex and often misunderstood condition.

It can have a significant impact on a person's quality of life.

Early diagnosis and management are crucial.

Pacing activities and managing symptoms are essential for improving function.

Support groups and counseling can provide emotional support and coping strategies.

It is important to seek care from healthcare professionals who are knowledgeable about ME/CFS.