Infiltrating Ductal Carcinoma

Summary about Disease


Infiltrating Ductal Carcinoma (IDC) is the most common type of breast cancer, accounting for approximately 70-80% of all invasive breast cancers. It originates in the milk ducts of the breast and then invades surrounding breast tissue. From there, it can potentially spread (metastasize) to other parts of the body through the lymphatic system or bloodstream.

Symptoms


A new lump or thickening in the breast or underarm area.

Change in the size or shape of the breast.

Nipple discharge (other than breast milk).

Nipple retraction (turning inward).

Dimpling or puckering of the breast skin.

Red, scaly, or swollen skin on the breast or nipple.

Pain in the breast (less common).

Swelling in all or part of the breast.

Causes


The exact causes of infiltrating ductal carcinoma are not fully understood, but several risk factors increase the likelihood of developing the disease:

Age: The risk increases with age.

Family history: Having a close relative with breast cancer.

Genetics: Inherited gene mutations (e.g., BRCA1, BRCA2).

Hormone exposure: Prolonged exposure to estrogen (e.g., early menstruation, late menopause, hormone therapy).

Obesity:

Previous breast conditions: Certain non-cancerous breast conditions.

Radiation exposure:

Alcohol consumption:

Dense breast tissue:

Never having been pregnant or having a first child later in life.

Medicine Used


Treatment for IDC typically involves a combination of approaches, and the specific medicines used depend on the stage of the cancer, hormone receptor status, HER2 status, and overall health of the patient. Common medications include:

Chemotherapy: Drugs to kill cancer cells throughout the body (e.g., anthracyclines, taxanes, cyclophosphamide, fluorouracil).

Hormone therapy: Drugs to block the effects of estrogen or lower estrogen levels (e.g., tamoxifen, aromatase inhibitors).

Targeted therapy: Drugs that target specific proteins or pathways involved in cancer growth (e.g., trastuzumab (Herceptin) for HER2-positive cancers, other HER2 inhibitors, CDK4/6 inhibitors).

Immunotherapy: Drugs that help the body's immune system fight cancer (e.g., pembrolizumab, atezolizumab) – used in certain advanced cases.

Is Communicable


Infiltrating Ductal Carcinoma is not communicable. It is not an infectious disease and cannot be spread from person to person.

Precautions


There are no specific precautions to prevent IDC, as the causes are complex and not fully understood. However, individuals can reduce their risk by:

Maintaining a healthy weight.

Limiting alcohol consumption.

Being physically active.

Discussing hormone therapy risks and benefits with their doctor.

Undergoing regular breast cancer screening (mammograms, clinical breast exams).

If high risk (family history or genetic mutations), considering risk-reducing medications or surgery.

How long does an outbreak last?


IDC is not an "outbreak" but a chronic disease process. Without treatment, it will continue to progress. With treatment, the duration of the treatment period and the patient's lifespan depend on many factors and the specific circumstances of the patient.

How is it diagnosed?


Physical exam: Doctor examines the breasts for lumps or other abnormalities.

Mammogram: X-ray of the breast to detect tumors or suspicious areas.

Ultrasound: Uses sound waves to create images of the breast tissue.

MRI: Magnetic resonance imaging provides detailed images of the breast.

Biopsy: A sample of tissue is removed and examined under a microscope to confirm the presence of cancer and determine its type and characteristics.

Other tests: If cancer is found, other tests like bone scan, CT scan, or PET scan may be used to see if the cancer has spread to other parts of the body (metastasis).

Timeline of Symptoms


The timeline of symptoms can vary significantly. Some individuals may notice a lump relatively quickly, while others may not experience any noticeable symptoms for a long time, especially with regular screening. The speed of tumor growth and symptom development depends on the individual tumor characteristics (e.g., grade, hormone receptor status, HER2 status).

Important Considerations


Early detection through regular screening is crucial for better treatment outcomes.

Treatment plans are individualized based on the specific characteristics of the cancer and the patient's overall health.

Ongoing monitoring and follow-up care are necessary after treatment to detect any recurrence or side effects.

Support groups and counseling can provide emotional and practical support for patients and their families.

Discuss all treatment options and potential side effects with your healthcare team.

Consider genetic testing if there is a strong family history of breast cancer or other related cancers.