Keratoderma climactericum

Summary about Disease


Keratoderma climactericum (also known as Haxthausen's disease) is a skin condition primarily affecting postmenopausal women. It's characterized by thickened, scaling skin on the palms and soles, often accompanied by painful fissures. The condition is associated with the hormonal changes of menopause but can occur in some premenopausal women and, rarely, in men.

Symptoms


Thickening of the skin (hyperkeratosis) on the palms and soles.

Dry, scaly skin.

Painful fissures (cracks) in the thickened skin, especially on the heels.

Redness or inflammation of the affected areas.

Discomfort or pain when walking or using the hands.

Possible itching.

Causes


Hormonal changes: The primary suspected cause is the decline in estrogen levels during menopause.

Genetic predisposition: There may be a genetic component making some individuals more susceptible.

Obesity: Higher BMI is associated with increased risk.

Poor circulation: May contribute.

Underlying skin conditions: Existing conditions may increase susceptibility.

Medicine Used


Topical Emollients (Moisturizers): To hydrate and soften the skin.

Topical Keratolytics: Such as urea, salicylic acid, or lactic acid to help remove thickened skin.

Topical Corticosteroids: To reduce inflammation and itching.

Topical Retinoids: To promote skin cell turnover.

Hormone Replacement Therapy (HRT): In some cases, HRT may be considered to address the underlying hormonal imbalance (requires consultation with a healthcare professional).

Calcipotriol: topical vitamin D analogue.

Oral Retinoids: In severe cases.

Is Communicable


No, Keratoderma climactericum is not communicable. It is not caused by an infection and cannot be spread from person to person.

Precautions


Regular moisturizing: Apply emollients frequently, especially after bathing.

Avoid harsh soaps and detergents: Use gentle, fragrance-free cleansers.

Wear appropriate footwear: Avoid shoes that rub or irritate the skin.

Protect hands: Wear gloves when doing housework or working outdoors.

Maintain a healthy weight: Obesity can exacerbate the condition.

Manage underlying conditions: If you have any skin conditions, ensure that they are managed.

Avoid prolonged standing: Minimize prolonged standing to avoid putting excessive pressure on the feet.

Gentle exfoliation: Gently remove dead skin cells with a pumice stone or exfoliating scrub after soaking the affected area.

Stay hydrated: Drink plenty of water to keep your skin hydrated.

How long does an outbreak last?


Keratoderma climactericum is often a chronic condition, meaning it can persist for a long time. The duration of symptoms can vary. Symptoms can be managed, but it may require ongoing treatment to control the thickening and cracking of the skin. Without management the condition will persist and worsen.

How is it diagnosed?


Physical examination: A doctor will examine the skin on the palms and soles.

Medical history: The doctor will ask about your medical history, including menopausal status and any other relevant conditions.

Skin biopsy: Rarely, a skin biopsy may be performed to rule out other conditions.

Ruling out other conditions: The doctor will rule out other conditions that can cause similar symptoms, such as fungal infections, psoriasis, and eczema.

Timeline of Symptoms


Onset: Symptoms typically begin around the time of menopause, but can occur earlier.

Gradual progression: The thickening of the skin usually develops gradually over time.

Fluctuations: Symptoms may fluctuate in severity depending on factors such as weather, activity level, and treatment adherence.

Chronic nature: Without management, the condition will likely persist indefinitely.

Important Considerations


Consultation with a healthcare professional: It's essential to consult a doctor or dermatologist for diagnosis and treatment.

Personalized treatment: Treatment should be tailored to the individual's specific symptoms and needs.

Long-term management: Keratoderma climactericum often requires long-term management to control symptoms and prevent complications.

Compliance with treatment: Adherence to the prescribed treatment plan is crucial for effective management.

Psychological impact: The condition can affect quality of life, so addressing any psychological distress is important.

Differential Diagnosis: Accurate diagnosis is crucial to rule out other similar conditions and to provide appropriate treatment.