Lichen Sclerosus

Summary about Disease


Lichen sclerosus is a chronic inflammatory skin condition that primarily affects the genital and anal areas. It can cause thin, white patches of skin, most commonly on the vulva in women and the foreskin in uncircumcised men. The condition can cause discomfort, itching, pain, and changes in the appearance of the affected skin.

Symptoms


Common symptoms include:

Smooth, white patches on the skin (often described as "parchment-like")

Itching (which can be severe)

Pain or discomfort

Thin, fragile skin that bruises easily

Blisters or ulcers

Painful intercourse (in women)

Constipation (due to anal involvement)

Tightening or shrinking of the foreskin (in men)

In severe cases, scarring can occur.

Causes


The exact cause of lichen sclerosus is unknown, but it is believed to be an autoimmune disorder where the immune system mistakenly attacks the skin. Genetic factors, hormonal imbalances, and prior skin damage may also play a role. It is not caused by poor hygiene or sexually transmitted infections.

Medicine Used


Topical corticosteroids: These are the primary treatment for lichen sclerosus and are used to reduce inflammation and itching. High-potency corticosteroids, such as clobetasol propionate, are commonly prescribed.

Topical calcineurin inhibitors: Tacrolimus or pimecrolimus can be used as an alternative treatment if corticosteroids are ineffective or cause side effects.

Emollients: These moisturizers help to soothe and protect the skin.

Testosterone cream: May be used for men with foreskin involvement.

Surgery: In severe cases, surgery may be needed to remove affected tissue.

Is Communicable


No, lichen sclerosus is not contagious and cannot be spread from person to person through any form of contact (sexual or otherwise).

Precautions


Avoid irritating the affected area.

Use gentle, fragrance-free cleansers and avoid harsh soaps.

Keep the area clean and dry.

Wear loose-fitting clothing.

Avoid scratching the affected area.

Follow your doctor's treatment plan carefully.

Regular self-exams to monitor for changes.

If sexually active, use lubricants during intercourse to reduce friction.

How long does an outbreak last?


Lichen sclerosus is a chronic condition, meaning that it can last for many years or even a lifetime. Without treatment, symptoms can persist and worsen. With proper treatment, symptoms can often be managed, and flare-ups can be minimized. The duration of a flare-up can vary from days to weeks, depending on the severity and response to treatment.

How is it diagnosed?


Lichen sclerosus is usually diagnosed through a physical examination of the affected area by a doctor. A skin biopsy may be performed to confirm the diagnosis and rule out other conditions, especially if the presentation is not typical.

Timeline of Symptoms


The onset of lichen sclerosus symptoms can be gradual or sudden. A typical timeline might look like this:

Early Stage: Appearance of small, white spots or patches. Mild itching or discomfort.

Progressive Stage: Patches enlarge and merge. Increased itching, pain, and skin fragility.

Advanced Stage: Skin becomes thin and parchment-like. Blisters, ulcers, and scarring may develop. Possible narrowing of the vaginal opening (in women) or foreskin (in men). It's important to note that not everyone experiences all stages or symptoms. Early diagnosis and treatment can help prevent the condition from progressing.

Important Considerations


Lichen sclerosus can increase the risk of squamous cell carcinoma (a type of skin cancer) in the affected area. Regular follow-up with a healthcare professional is crucial for monitoring and early detection.

Children can also be affected by lichen sclerosus, although it is more common in postmenopausal women.

Psychological impact: The condition can have a significant impact on quality of life, including sexual function and self-esteem. Support groups and counseling may be helpful.

Adherence to treatment is important to prevent the condition from progressing and to manage symptoms.

Circumcision may be recommended for men with lichen sclerosus affecting the foreskin.