Summary about Disease
Lobular carcinoma in situ (LCIS) is an uncommon condition where abnormal cells form in the lobules (milk-producing glands) of the breast. While LCIS isn't considered a true cancer, it indicates an increased risk of developing invasive breast cancer in the future, in either breast. It is considered a marker of increased risk, rather than a cancer in itself.
Symptoms
LCIS typically causes no noticeable symptoms. It is usually discovered incidentally during a biopsy performed for another reason, such as an abnormal mammogram finding or a palpable lump that turns out to be something else.
Causes
The exact cause of LCIS is unknown. It is thought to develop when genetic mutations cause cells in the breast lobules to grow abnormally. Hormones may play a role in the development of LCIS.
Medicine Used
LCIS itself is generally not treated with medication. However, individuals diagnosed with LCIS may be prescribed medications like tamoxifen or raloxifene as preventive (chemoprevention) therapy to reduce the risk of developing invasive breast cancer. These medications block the effects of estrogen in breast tissue.
Is Communicable
No, LCIS is not a communicable or contagious disease. It cannot be spread from person to person.
Precautions
There are no specific precautions to prevent LCIS. Because it is a risk indicator, rather than a disease, management focuses on risk reduction strategies:
Increased surveillance: More frequent breast exams and imaging (mammograms, MRIs) are recommended to detect any potential cancers early.
Chemoprevention: Discussing medications like tamoxifen or raloxifene with your doctor.
Lifestyle modifications: Maintaining a healthy weight, exercising regularly, limiting alcohol consumption, and not smoking can reduce overall breast cancer risk.
Prophylactic mastectomy: In rare cases, some women with a very high risk may consider preventive (prophylactic) mastectomy.
How long does an outbreak last?
LCIS is not an "outbreak" condition. It is a presence of abnormal cells. There is no set duration. The risk of developing invasive cancer persists throughout life.
How is it diagnosed?
LCIS is typically diagnosed after a breast biopsy is performed for another reason, such as an abnormal mammogram or a palpable lump. The biopsy sample is examined under a microscope by a pathologist, who identifies the abnormal cells characteristic of LCIS.
Timeline of Symptoms
LCIS itself typically has no symptoms. The timeline is usually:
No symptoms: Most individuals are unaware they have LCIS.
Incidental discovery: LCIS is found during a biopsy for another breast concern.
Increased monitoring begins: After diagnosis, increased surveillance starts.
Potential development of invasive cancer: The timeline for this is variable and may never occur.
Important Considerations
LCIS is not cancer: It is a marker of increased risk.
Increased risk of invasive cancer: It significantly elevates the lifetime risk of developing breast cancer.
Discuss risk reduction strategies: Talk to your doctor about surveillance, chemoprevention, and lifestyle modifications.
Regular follow-up is crucial: Adhere to the recommended screening schedule.
Emotional impact: A diagnosis of LCIS can cause anxiety. Seek support from healthcare professionals, support groups, or loved ones.