Oral Allergy Syndrome

Summary about Disease


Oral Allergy Syndrome (OAS), also known as pollen-food allergy syndrome, is a type of allergic reaction that occurs when individuals with pollen allergies experience localized allergic symptoms in the mouth after eating certain fresh fruits, vegetables, or nuts. The proteins in these foods are similar to those found in specific pollens, causing the immune system to react.

Symptoms


Symptoms are generally mild and localized to the mouth, lips, tongue, and throat. Common symptoms include:

Itching or tingling of the lips, tongue, or palate

Mild swelling of the lips, tongue, or throat

Scratchy or sore throat

Occasionally, skin rash around the mouth In rare cases, more severe symptoms like difficulty breathing or swallowing can occur, requiring immediate medical attention.

Causes


OAS is caused by cross-reactivity between pollen allergens and similar proteins found in certain raw fruits, vegetables, and nuts. The most common pollen triggers include:

Birch pollen (often associated with apples, cherries, almonds, carrots)

Ragweed pollen (often associated with bananas, melons, cucumbers)

Grass pollen (often associated with tomatoes, melons, oranges)

Medicine Used


Treatment primarily focuses on managing symptoms. Common medications include:

Antihistamines: To relieve itching and swelling.

Epinephrine: (EpiPen) In rare cases of severe reactions (anaphylaxis).

Is Communicable


No, Oral Allergy Syndrome is not communicable. It is an allergic reaction and not an infectious disease.

Precautions


Avoidance: Identify and avoid the specific raw fruits, vegetables, or nuts that trigger symptoms.

Cooking: Cooking often denatures the reactive proteins, making the foods safe to eat.

Peeling: Peeling fruits and vegetables may reduce the amount of allergen.

Allergy Testing: Undergo allergy testing to identify specific pollen and food triggers.

Carry Epinephrine: If you have a history of severe reactions, carry an epinephrine auto-injector.

How long does an outbreak last?


Symptoms are usually short-lived, resolving within minutes to an hour after exposure to the trigger food is stopped.

How is it diagnosed?


Diagnosis is typically based on:

Medical History: Detailing symptoms after eating certain foods.

Skin Prick Testing: Testing for pollen and food allergies.

Blood Tests: Measuring IgE antibodies to specific allergens.

Oral Food Challenge: In some cases, a controlled oral food challenge may be performed under medical supervision.

Timeline of Symptoms


1. Ingestion: Symptoms begin almost immediately upon eating the triggering food. 2. Onset: Itching, tingling, or mild swelling in the mouth, lips, and throat develop within minutes. 3. Resolution: Symptoms typically resolve within minutes to an hour after stopping consumption of the trigger food.

Important Considerations


Severity: Symptoms can vary in severity from mild to potentially life-threatening (though this is rare).

Cross-Reactivity: Individuals may react to multiple foods due to cross-reactivity.

Pollen Season: Symptoms may be worse during peak pollen seasons.

Progression: OAS can develop at any age, even if the individual has previously tolerated the food.

Physician Consultation: It's crucial to consult with an allergist for proper diagnosis and management.