Papilloma

Last update: June 10, 2025

Summary about Disease


Papillomas are benign (non-cancerous) skin growths caused by the human papillomavirus (HPV). They can appear anywhere on the body but are most commonly found on the skin, mucous membranes (like inside the mouth or nose), and genitals. Papillomas are often referred to as warts or skin tags, depending on their appearance and location. Not all HPV types cause cancer, but some can increase the risk of certain cancers, particularly cervical cancer.

Symptoms


Symptoms vary based on the type and location of the papilloma:

Skin warts: Raised, rough bumps on the skin, often on hands and feet.

Plantar warts: Warts on the soles of the feet, which can be painful due to pressure.

Genital warts: Flesh-colored, cauliflower-like growths on the genitals, anus, or groin.

Oral papillomas: Small, flesh-colored or white growths in the mouth.

Skin Tags: Small, soft, flesh-colored growths that hang off the skin.

Causes


Papillomas are caused by infection with the human papillomavirus (HPV). HPV is transmitted through direct contact with an infected person or contaminated surfaces. Different HPV types cause different types of papillomas. The virus enters the body through cuts or breaks in the skin.

Medicine Used


4. Medicine used Treatment options vary depending on the type, location, and size of the papilloma:

Topical medications: Salicylic acid, imiquimod, podophyllin resin, and trichloroacetic acid are used to destroy or stimulate the immune system to fight warts.

Cryotherapy: Freezing the wart off with liquid nitrogen.

Electrocautery: Burning the wart off with an electric current.

Surgical excision: Cutting the wart off with a scalpel.

Laser treatment: Using a laser to destroy the wart tissue.

For Genital warts: Prescription creams like imiquimod, podophyllotoxin, or sinecatechins are often prescribed.

Is Communicable


Yes, papillomas caused by HPV are highly communicable. The virus spreads through direct skin-to-skin contact, sexual contact (for genital warts), and contact with contaminated objects (like towels or razors). Autoinoculation (spreading the virus to other parts of your own body) is also possible.

Precautions


Vaccination: HPV vaccines are available to protect against certain types of HPV that cause genital warts and some cancers.

Avoid direct contact: Avoid touching warts on yourself or others.

Hygiene: Wash hands frequently, especially after touching potentially contaminated surfaces.

Avoid sharing personal items: Don't share towels, razors, or other personal items.

Safe sex practices: Use condoms to reduce the risk of spreading genital warts (although condoms don't provide complete protection).

Keep skin dry and healthy: HPV is more likely to infect damaged or moist skin.

Cover wounds: Cover any cuts or breaks in the skin to prevent HPV from entering.

How long does an outbreak last?


The duration of a papilloma outbreak varies:

Warts: Can disappear on their own within months to years, but treatment can speed up the process.

Genital warts: May disappear on their own, remain stable, or increase in size and number. Treatment can help to remove them.

Recurrence: Papillomas can recur even after treatment, as the virus can remain dormant in the body.

How is it diagnosed?


Visual examination: A doctor can usually diagnose papillomas by looking at them.

Biopsy: A small sample of the growth may be taken and examined under a microscope to confirm the diagnosis and rule out other conditions.

HPV testing: For genital warts, HPV testing may be performed to identify the specific HPV type.

Colposcopy: For women with genital warts, a colposcopy may be performed to examine the cervix for abnormalities.

Timeline of Symptoms


9. Timeline of symptoms

Incubation period: The time between HPV infection and the appearance of papillomas can range from weeks to months.

Initial appearance: Small, often painless growths appear on the skin or mucous membranes.

Progression: The growths may remain small, grow larger, or multiply over time.

Resolution: Papillomas may disappear on their own, remain stable, or require treatment for removal.

Important Considerations


Cancer risk: Certain HPV types are associated with an increased risk of cervical cancer, anal cancer, penile cancer, and oral cancer. Regular screening (Pap smears for women) is important.

Immunocompromised individuals: People with weakened immune systems are more susceptible to HPV infection and may have more difficulty clearing the virus.

Psychological impact: Papillomas, especially genital warts, can cause embarrassment, anxiety, and relationship problems.

Treatment side effects: Some treatments for papillomas can cause side effects such as pain, scarring, and changes in skin pigmentation.

Prevention: HPV vaccination is the most effective way to prevent HPV infection and related cancers.