Twenty-nail dystrophy

Summary about Disease


Twenty-nail dystrophy is a nail disorder affecting all twenty fingernails and toenails. It is characterized by changes in the nail surface, giving them a rough, ridged, or sandpaper-like appearance. It's often idiopathic (cause unknown), but can be associated with other skin conditions.

Symptoms


Ridging: Longitudinal (lengthwise) ridges on the nail surface are common.

Pitting: Small depressions or pits may appear on the nail plate.

Lusterless Nails: Nails lose their normal shine and become dull.

Thinning: The nails may become thinner and more fragile.

Splitting: Nail splitting or brittleness can occur.

Sandpaper-like Texture: The surface of the nails can feel rough to the touch.

Color Changes: The nails may become opaque, yellow, or gray.

Causes


The cause is often unknown (idiopathic). However, it can be associated with:

Lichen Planus: An inflammatory skin condition.

Alopecia Areata: An autoimmune disorder causing hair loss.

Psoriasis: A skin condition causing scaly, itchy patches.

Eczema: A skin condition causing itchy, inflamed skin.

Atopic Dermatitis: A type of eczema.

Genetic Factors: In some cases, there may be a genetic predisposition.

Medicine Used


Treatment is not always necessary, especially if the condition is mild and asymptomatic. When treatment is pursued, options may include:

Topical Corticosteroids: Applied to the nail folds to reduce inflammation.

Oral Corticosteroids: May be prescribed in severe cases, but side effects are a concern.

Topical Tretinoin: A retinoid that can help improve nail appearance.

Biotin Supplements: Some studies suggest biotin may improve nail health, but evidence is limited.

Calcipotriol: Topical vitamin D analogue.

Is Communicable


No, twenty-nail dystrophy is not communicable. It is not caused by an infection and cannot be spread from person to person.

Precautions


Avoid Trauma: Protect nails from injury to prevent further damage.

Moisturize: Keep nails and surrounding skin moisturized to prevent dryness and cracking.

Gentle Nail Care: Avoid harsh chemicals, excessive filing, or artificial nails that can worsen the condition.

Identify and Treat Underlying Conditions: If the condition is associated with another skin disorder, managing that condition can improve nail health.

How long does an outbreak last?


The duration of twenty-nail dystrophy is variable. It can be a chronic condition lasting for years, or it may resolve spontaneously over time, particularly in children. There is no defined "outbreak" period, but rather a gradual onset and progression of symptoms. In some cases, it can last months to years.

How is it diagnosed?


Diagnosis is primarily based on:

Clinical Examination: A dermatologist will examine the nails and assess the characteristic features.

Medical History: Reviewing the patient's medical history to identify any associated conditions.

Nail Biopsy: In some cases, a nail biopsy may be performed to rule out other nail disorders and confirm the diagnosis.

Timeline of Symptoms


The onset is usually gradual.

Early Stages: Subtle changes in nail texture or color may be noticed.

Progression: Over time, ridges, pits, and other characteristic features become more prominent.

Chronic Stage: The condition may persist for months or years with fluctuating severity.

Important Considerations


Differential Diagnosis: It is important to differentiate twenty-nail dystrophy from other nail disorders, such as onychomycosis (fungal nail infection) or psoriasis.

Psychological Impact: The appearance of the nails can be distressing for some individuals, affecting their self-esteem and quality of life.

No Cure: There is no definitive cure for twenty-nail dystrophy, and treatment is aimed at managing symptoms and improving nail appearance.

Spontaneous Resolution: It can resolve spontaneously, especially in children.